22 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Algorithm Signs of anemia ... Anemias (AIHAs) ... Anemias (AHAs) ... #Anemias #Differential
Anemia - Hemolysis Diagnostic Algorithm
Autoimmune hemolytic anemia
Microangiopathic hemolytic anemia
Probable thalassemia

Dr. Eric Strong @DrEricStrong - Strong Medicine
Anemia - Hemolysis ... anemia Microangiopathic ... hemolytic anemia ... #Anemia #Algorithm ... #differential #
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
fragmentation hemolysis ... toxin-mediated hemolytic-uremic ... • Mechanical hemolysis ... anemia" • HELLP ... #hemolysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... Intravascular Hemolysis ... hemolytic anemia ... purpura (TTP), Hemolytic ... #anemia
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... hemolytic anemia ... hemolytic anemia ... #hemolytic #anemia ... #Hematology #Pathology
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... → Sickle Cell anemia ... Immune mediated hemolysis ... hemolytic anemia ... #Anemia #Differential
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Iron deficiency anemia ... Hemolytic Anemia ... spherocytosis, Autoimmune hemolytic ... Cold autoimmune hemolytic ... #differential #
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Bleed • Hemolysis ... Fragments • Microangiopathic ... Hemolytic Anemias ... #Normocytic #Anemia
Causes of Hemolytic Anemia - Differential Diagnosis
Inherited
 • Membrane
 • Internal
    - Hemoglobin
Causes of Hemolytic ... Anemia - Differential ... Environment - Microangiopathic ... Sophia_Hayes_MD #Hemolytic ... #Anemia #Differential
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Megaloblastic Anemia ... hemolytic anemia ... Microspherocytes: Autoimmune hemolytic ... anemia Sickled ... interpretation #clinical #anemia