12 results
oncology anemia blood causes mds myelodysplastic product reactions adultonset coagulation dic differential disease disseminated hemophagocytic hlh intravascular lymphohistiocytosis myelodysplasia neutropenia
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Symptomatic anemia Diagnosis ... #Anemia #diagnosis ... #management #treatment ... #hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP) Diagnosis of TTP: • Rare and severe, ADAMTS13 deficiency • Autoimmune
Purpura (TTP) Diagnosis ... severe, ADAMTS13 deficiency ... Thrombocytopenic #Purpura #management ... #treatment #rheumatology ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... dys- (abnormal) -plastic ... only curative treatment ... #Management #treatment ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
anemia, GATA2 deficiency ... , CTLA4 deficiency ... anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... mevalonate kinase deficiency ... Stills #Disease #diagnosis ... #management #treatment ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... Cellular immune deficiency ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
thrombopoietin deficiency ... + Bleeding Treatment ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Causes • Anemia • Aplastic ... or folic acid deficiency ... • Copper deficiency ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... hypertension and/or drug treatment ... anemia-rare - Copper deficiency-rare ... white blood cell aplasia ... #causes #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
recipients w/ IgA deficiency ... due to marrow aplasia ... #Transfusion #diagnosis ... #management #hematology
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