26 results
causes oncology algorithm atlas classification extravascular hemolysis leukemia lymphocytic morphology rbc thrombocytosis workup agglutinin aplastic apml arteritis ascorbicacid bandemia bloodcell
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) (e.g. lupus, CLL ... G6PD deficiency) ... #Hemolytic #Intravascular ... #Causes #differential ... #diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Hemolysis - Differential ... • Sickle cell ... anemia • ... Differential #Diagnosis ... Algorithm #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... • Bleeding • Hemolysis ... Infection) High ... #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
spherocytosis, Hemolytic ... , Disseminated intravascular ... Morphology #Atlas #key #diagnosis ... #differential # ... hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... , deficiency anemia ... : Chronic infections ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... specifically: iron deficiency ... , hemolysis, hemorrhage ... myeloid leukemia (CML ... #hematology #secondary
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
anemia, Chronic ... Microangiopathic Hemolytic ... Cold autoimmune hemolytic ... RBC #Morphology #differential ... #diagnosis #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
defects (e.g. sickle cell ... anemia, G6PD deficiency ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Consider sickle cell ... #Anemia #Differential ... #workup #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Clinical Presentation ... Diagnosis: • hemolytic ... younger pts) Differential ... the RBCs causing intravascular ... #anemia #hematology
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