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differential rheumatology erythematosus lupus systemic causes criteria oncology purpura signs symptoms algorithm autoantibodies bruising chronic cll dermatology disorders eularacr hodgkins
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... genotypes): SS, SC, SE ... Schistocytes, thrombocytopenia ... #workup #hematology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... ANEMIA - LEUKOPENIA ... (<1000/MM3) - THROMBOCYTOPENIA ... anemia #Diagnosis ... #Rheumatology #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... test, ANA (e.g., SLE ... changes), high MCV anemia ... #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... activity is the diagnostic ... result in severe anemia ... anemia Indirect ... #Workup #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... - CTD (SLE) ... #hematology #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Systemic Lupus (SLE ... ) Blood (75%): Anemia ... Leucopenia/lymphopenia, Thrombocytopenia ... signs #symptoms #diagnosis ... #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... domain: Leukopenia, Thrombocytopenia ... , Autoimmune hemolysis ... #Criteria #SLE ... Erythematosus #diagnosis
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Neurological 12% - Thrombocytopenia ... Lymphadenopathies 7% - Hemolytic ... anemia 4% - Myositis ... involvement 3% SLE-Related ... Lupusreference #SLE
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
) - SLE ( ... Non-immune - Haemolytic ... Henoch—Schönlein purpura, SLE ... #Causes #peds #pediatrics ... #diagnosis #differential
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... • Neutropenia, anemia ... , thrombocytopenia ... #workup #oncology ... #hematology
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