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oncology causes symptoms chronic classification cll erythematosus leukemia lupus lymphocytic mcv purpura sle syndrome systemic thrombocytosis workup activation agglutinin anemias
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Diagnosis Algorithm ... Signs of anemia ... #Anemias #Differential ... #Diagnosis #Algorithm ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Diagnosis Algorithm ... #Anemia #Differential ... #Diagnosis #Algorithm ... #workup #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... , Vasculitides, ... #Diagnosis #Algorithm ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... microangiopathy: Thrombotic thrombocytopenic ... Extravascular #Causes #differential ... #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Myelofibrosis Infectious ... Iron deficiency anemia ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Diagnosis Algorithm ... HUS • DIC • Vasculitis ... • Infection ... Diagnosis #Algorithm ... #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... Macroangiopathic, Infections ... Non-megaloblastic: Liver disease ... Diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... #Diagnosis #hematology ... #rheumatology #
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Diagnosis Algorithm ... • Bleeding • Hemolysis ... Inflammation, Chronic Infection ... #Diagnosis #Algorithm ... #Causes #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Clinical Presentation ... Diagnosis: • hemolytic ... #hemolytic #anemia ... #hematology #diagnosis
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