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Hyperkalemia Hypokalemia - Differential Diagnosis and Management Algorithm

Dr Pravin Patel

#Hypokalemia #Hyperkalemia #potassium #differential #diagnosis #management
Hyperkalemia Hypokalemia ... - Differential ... Diagnosis and Management ... potassium #differential ... #diagnosis #management
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... • G-CSF • Hypokalemic ... periodic paralysis ... #Differential # ... nephrology #low #potassium
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
Hypokalemia - Differential ... proliferation - Hypokalemic ... periodic paralysis ... #Differential # ... Diagnosis #Low #Potassium
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
patients with hypokalemia ... the basis of the potassium-to-creatinine ... periodic paralysis ... #urine #potassium ... #differential #
Thyrotoxic Periodic Paralysis - Illness Script
 • Epidemiology: Asian men age 20-30 with hyperthyroidism of any
Thyrotoxic Periodic ... Labs/lmaging: Hypokalemia ... • Treatment: Potassium ... hyperthyroidism, Potassium ... #Thyrotoxic #Periodic
Hypokalaemia:

The gradual fall in serum potassium level is reflected electrocardiographically by the following features:

1. Gradual decrease
Hypokalaemia: ... fall in serum potassium ... leads V2-V4 #Clinical ... #Cardiology #ECG ... #EKG #UWaves #Hypokalemia
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Hyperkalemia: Diagnostic ... Normal, Renin High ... hypoplasia Aldosterone high ... • Type 1 #Hyperkalemia ... #differential
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... phlebotomy High ... Periodic paralysis ... #differential # ... #high #nephrology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
8.0 mg/dL • Potassium ... Calcium ≤ 7.0 mg/dL Clinical ... hydroxide • Hyperkalemia ... treatment • Hypocalcemia ... TLS #diagnosis #management
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Hyperkalemia Differential ... TTKG should be high ... #Differential # ... Algorithm #causes #potassium ... #high #pathophysiology