51 results
Algorithm for the Diagnosis and Workup of Hemolytic Anemia

By Dr. Kylie Adamek @KylieAdamek

#Hemolytic #Anemia #Algorithm #Differential
the Diagnosis and ... Workup of Hemolytic ... Anemia #Algorithm #Differential ... #Diagnosis #Workup ... #Hematology #Hemolysis
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
- Differential ... Signs of anemia and ... Reticulocytes • Abnormal peripheral ... #Anemias #Differential ... Diagnosis #Algorithm #hematology
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... observation of the peripheral ... thrombocytopenic purpura/hemolytic ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... usually IgG) (e.g. lupus ... disease, Copper and ... #differential # ... diagnosis #hematology
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
12-13 g/dL, • ANC ... BMP, uric acid, peripheral ... ↑ Destruction (hemolysis ... Diagnosis #Algorithm #hematology ... #workup
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Diagnosis Algorithm Peripheral ... → Refer to hematology ... for workup, including ... blood loss, Acute hemolysis ... Diagnosis #Algorithm #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... Hemolysis - Differential ... Extravascular #Differential ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm
 • Reactive (Inflammatory / Infectious)
 •
Causes of Diffuse ... and Localized Lymphadenopathy ... - Differential ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
- Differential ... Inflammatory • Systemic Lupus ... Serum Sickness Hemolytic ... Spleen #Enlarged #Differential ... #Hematology