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differential oncology causes chronic classification lymphocytic management anemia basophilia cancer enlarged gap globulin hemeonc hemolytic hodgkins lymphoma lymphomas lymphoproliferative mds
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Diagnosis Framework ... Myeloproliferative Disorders ... Colitis and Crohn’s Disease ... #Differential #Diagnosis ... #causes #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... eosinophilia, basophilia ... Significant ↓ PLT: Petechiae ... #Hematology #Oncology ... #Diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Chronic Myelogenous Leukemia ... • Rheumatic disorders ... • Celiac disease ... effect following treatment ... #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... lymphoproliferative disorders ... microglobulin Treatment ... #diagnosis #workup ... #oncology #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Algorithm Infectious ... • Lymphoma • Leukemia ... Myeloproliferative disorders ... • Sickle Cell ... #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Consider sickle cell ... thalassemia, S Lepore • Basophilic ... Consider RBC membrane disorder ... #Algorithm #workup ... #hematology #testing
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... History of bleeding (petechiae ... not required in all ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... in adults • Disorder ... chemotherapy for low-risk disease ... uw_IMresidency #CLL ... #oncology #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... - Differential Diagnosis ... Algorithm Hodgkin ... Treated Like Acute Leukemias ... pathophysiology #Hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Rare Disorder: ... - Rash: multiple ... Treatment: - Systemic ... #dermatology #oncology
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