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differential oncology causes algorithm syndrome aplastic intravascular lymphocytic mds myelodysplastic acquired atlas basophilia basophils blood bloodcell cancer classification common cvid
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Myelogenous Leukemia ... • Rheumatic disorders ... • Celiac disease ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... inflammatory disorders ... myeloid leukemia ... (CML) - Dr. ... #Causes #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... #hematology #Markers ... #Differential #Diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... • Infections: Chronic ... #Algorithm #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... -> Invade Skin: ... #Hematology #Oncology ... #Diagnosis
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
inherited bleeding disorder ... bruising • Skin ... factor VIII) Treatment ... #Disease #Diagnosis ... #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
• Lymphoma • Leukemia ... Myeloproliferative disorders ... vera, essential thrombocytosis ... • Sickle Cell ... Algorithm #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... cells can indicate disease ... • Neutropenia, anemia ... #Leukemia #diagnosis ... workup #oncology #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
and Management ... thrombocythemia), Autoimmune disease ... #Acquired #vonWillebrand ... #Management #treatment ... #hematology #differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... , coagulation disorders ... - Hemolytic anemia ... #hematology #rheumatology ... #nonpalpable #dermatology
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