19 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... : • Most common ... #Chronic #Lymphocytic ... #Leukemia #diagnosis ... workup #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... #Chronic #Lymphocytic ... #hematology #hemeonc ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... (Chronic Lymphocytic ... -> Invade Skin: ... #Hematology #Oncology ... #Diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Myelogenous Leukemia ... • Rheumatic disorders ... • Celiac disease ... effect following treatment ... #Causes #Hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential ... Diagnosis Algorithm ... Treated Like Acute Leukemias ... Classification #pathophysiology ... #Hematology #Diagnosis
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Myeloproliferative Disorders ... : • Chronic myeloid ... leukemia (CML) ... Colitis and Crohn’s Disease ... #hematology #basophils
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... to impaired B-cell ... Granulomatous lymphocytic ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
promyelocytic leukemia ... • Severe Liver Disease ... #diagnosis #causes ... #treatment #management ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... • Induce blast cell ... initiation • Differential ... #management #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... Diagnosis Framework ... gingivitis or gingival leukemic ... defects in the common ... #Diagnosis #Hematology