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differential oncology anemia syndrome workup aplastic blood bruising chronic classification intravascular lymphocytic mds myelodysplastic pathophysiology product reactions antinxp2 antinxp2dm arterial
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Differential Diagnosis ... Algorithm Thrombocytopenia ... #Algorithm #Causes ... #Hematology
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... #Differential #Diagnosis ... #Algorithm #Causes ... #Hematology #coagulation ... #disorders
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Chronic Myelogenous Leukemia ... • Rheumatic disorders ... • Celiac disease ... #Algorithm #Causes ... #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... -> AML: Blast crises ... -> Invade Skin: ... #Hematology #Oncology ... #Diagnosis
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
• Lymphoma • Leukemia ... Myeloproliferative disorders ... • Sickle Cell ... #Algorithm #Causes ... #Hematology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
Von Willebrand Disease ... disorder Clinical ... bruising • Skin ... factor VIII) Treatment ... #Diagnosis #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... , coagulation disorders ... disorders CAUSES ... #hematology #rheumatology ... #nonpalpable #dermatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... cells can indicate disease ... lymphoproliferative disorders ... microglobulin Treatment ... #oncology #hematology
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
- Differential Diagnosis ... Myeloproliferative Disorders ... Colitis and Crohn’s Disease ... #Differential #Diagnosis ... #causes #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... - History of bleeding ... PT, aPTT(liver disease ... not required in all ... #hematology
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