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lysis tumor anemia aplastic apml chronic cll differentiation emergencies gravis hemophagocytic hlh leukemia leukostasis lymphocytic lymphohistiocytosis mds myasthenia myelodysplastic neurology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
of Tumor Lysis Syndrome ... (TLS) and Treatment ... #TumorLysis #Syndrome ... #TLS #diagnosis ... #management #oncology
Tumor Lysis Syndrome - Workup and Management Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... - Workup and Management ... of the above Treatment ... #diagnosis #management ... #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... only curative treatment ... Myelodysplastic #Syndrome ... #Management #treatment ... #hematology #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... antibiotics TLS ... ): - Hematologic ... low Ca - q8 h TLS ... #HemeOnc #Diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
organ damage • Treatment ... leukapheresis - TLS ... Low calcium • Treatment ... #TLS #diagnosis ... #management #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... transformation) Treatment ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Renal Failure Treatment ... #management #hematology ... #oncology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Generalized fatigue - ALS ... myasthenia Diagnosis ... immunosuppressants - Meds ... Myasthenia #Gravis #diagnosis ... #management #neurology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome ... Treatment Approach ... #Management #Hematology ... #HemeOnc
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