20 results
Sarcoidosis - Skin Manifestations

This is a quick overview of some of the cutaneous manifestations of sarcoidosis.
Sarcoidosis - Skin ... of some of the cutaneous ... Sarcoid Plaques • Lupus ... differential #treatment #photo ... #dermatology #skinrash
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Rare (SSA+ for cutaneous ... Discontinuation of causal ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... response -> Subacute cutaneous ... hair follicles -> causes ... inflammation on skin ... endothelium) & Decr blood
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
intake) • Target blood ... Insufficient blood ... Measurement #SLE #rheumatology ... pharmacology #levels #lupus ... #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... autoantibodies that will cause ... thrombosis and/or blood-brain ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... such as systemic lupus ... pulses, bruis, or blood ... Large Vessel: Blood ... differential #diagnosis #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Henoch-Schönlein purpura) • Cutaneous ... (e.g. systemic lupus ... classification #rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Syndrome) is a skin ... Most common extra cutaneous ... Causes: - Idiopathic ... ’s syndrome - Lupus ... neutrophils in the blood
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
DERMATOMYOSITIS Cutaneous ... ulcerations • Skin ... onset [33-74%] • Blood ... • Skin vasculopathies ... Dermatomyositis #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... involvement (2%) Cutaneous ... Treat primary cause ... #treatment #management ... #hematology