10 results
AKI in Cirrhosis - Hepatorenal Syndrome Management Algorithm

DOI: 10.1136/bmj.m2687

#AKI #Cirrhosis #Hepatorenal #Syndrome #HRS #Management #Algorithm #nephrology
AKI in Cirrhosis ... - Hepatorenal Syndrome ... Management Algorithm ... #Hepatorenal #Syndrome ... #Algorithm #nephrology
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
for Management ... of Cirrhosis • ... ascites removed • Acute ... antibiotics • Hepatorenal ... syndrome - 1g/
Hepatorenal Syndrome Treatment
Volume expansion: 
 • Albumin (typical dose = 1g/kg on day 1 +/- day
Hepatorenal Syndrome ... expansion: • Albumin ... #Syndrome #Treatment ... #management #HRS ... #nephrology
Hepatorenal Syndrome - Diagnosis and Management Summary
Who gets HRS?
 • Decompensated cirrhosis
 • Typically with existing
Hepatorenal Syndrome ... Diagnosis and Management ... Decompensated cirrhosis ... #Syndrome #HRS ... #Diagnosis #Management
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
encephalopathy, and hepatorenal ... syndrome Clues ... INR, bilirubin, albumin ... • Budd Chiari syndrome ... /acute hepatitis
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... liver disease: cirrhosis ... hepatitis, or acute ... - IV albumin ... #HRS #Hepatorenal
Acute Kidney Injury (AKI) - Management Principles
Prerenal - Correct hemodynamic derangements:
 • If low preload →
Acute Kidney Injury ... (AKI) - Management ... - inotropes • Hepatorenal ... syndrome → Treat ... + midodrine + albumin
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome ... irrigation • Management ... Torsemide) • Acute ... hyperaldosteronism • Acute ... Excretion #Diuresis #Nephrology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
osteomyelitis or skin ... , neutropenia, cirrhosis ... organism into the skin ... Mouth, throat, skin ... Fungal #Diagnosis #Management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Total Protein - Albumin ... concentration minus albumin ... gammopathy, and skin ... changes (POEMS syndrome ... Liver disease: Cirrhosis