27 results
diagnosis rheumatology oncology dermatology clinical gastroenterology anemia aplastic disease emergencies hemeonc hemophagocytic hepatology hlh indications lymphohistiocytosis mds myelodysplastic activation apml
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... risk-stratification • Risks: infection ... only curative treatment ... Myelodysplastic #Syndrome ... #treatment #hematology
Systemic Inflammatory Response Syndrome (SIRS) • Non-specific (infections vs non-infectious) • ≥2 of the following: o Temp >38°C or <36°C o HR >90 bpm o RR
Inflammatory Response Syndrome ... Non-specific (infections ... vs non-infectious ... host response to infection ... recognition & treatment
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
: • Recurrent infections ... megaloblastic anemia Treatment ... (transfusions, antibiotics ... Anemia #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... can mimic common infections ... : • Infection ... rapidly, and empiric antibiotic ... #treatment #hematology
Invasive Fungal Infection (IFI) Invasive fungal infections are severe infections in which fungal pathogens invade normally sterile
Invasive Fungal Infection ... Invasive fungal infections ... are severe infections ... with neutropenia, hematologic ... of bloodstream infections
Vancomycin induced Leukocytoclastic Vasculitis (LCV) of the Hand 70 M vertebral osteomyelitis on vancomycin and cefepime for
including drugs, infections ... Indiana University Infectious ... Vasculitis #LCV #Hand #skinrash ... #dermatology #clinical ... #photo
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Neutropenia - recurrent infections ... - β-lactam antibiotics ... Idiopathic • Infections ... aplastic anemia Treatment ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Differential Diagnosis: Infection ... APML #diagnosis #management ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... isoniazid) • Antibiotics ... • Parvovirus infection ... factor (GCSF) treatments ... #diagnosis #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
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