14 results
diagnosis management differential sle erythematosus hcq hydroxychloroquine neurology systemic adverseeffects algorithm altered ams ana anca antibodies antibody antineutrophil antinuclear benefits
Hypertension and Altered Mental Status (AMS) - Differential Diagnosis Framework Hypertension: • Hypertensive emergency • Hypertensive encephalopathy
Pre-Eclampsia Renal ... Acute/Chronic renal ... failure • Renal ... Vasculitis • Lupus ... • Scleroderma renal
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Meningitis, Myelopathy, Encephalopathy ... autoantibodies that will cause ... Puncture, EEG Treatment ... CNS #neurology #rheumatology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... • Diabetes • Pituitary ... Metabolic • Renal ... Myasthenia Gravis Pharmacologic ... Chronic Fatigue Syndrome
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
• Special cases ... (e.g. renal failure ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... severe disease & renal ... severe disease Treatment ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... antiphospholipid syndrome ... S - Systemic Lupus ... Erythematosus (total 50, renal ... #differential #hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... • Sjögren syndrome ... polyangiitis without renal ... ANCA+ 30-60% • Renal-limited ... antibodies #diagnosis #rheumatology
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
and Benefits in Lupus ... of renal or hepatic ... Risks #Benefits #Lupus ... #pharmacology # ... #sideeffects #rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Posterior Reversible Encephalopathy ... Immunosuppressive agents, Renal ... the underlying cause ... • Treatment of ... with AEDs until cause
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Agents Regulating Renal ... Kidney stones caused ... Inhibitors of Renal ... Tolvaptan) • Treatment ... #Diuretics #Renal
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