12 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Direct renin inhibitor ... ) inhibitors (Lisinopril ... • Exogenous (KCL ... differential #diagnosis #pathophysiology ... #pharmacology #
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Serotonin Reuptake Inhibitors ... SSRIs #Serotonin #Inhibitors ... #Pathophysiology ... #Pharmacology # ... Psychiatry #Diagnosis #Signs
Atopic Dermatitis - Topical Treatment Options 
First Line: Topical Corticosteroids 
  - High Potency: Betamethasone
therapy is non-pharmacologic ... the first line pharmacologic ... If all topical products ... #Medications #Pharmacology ... #Dermatology #Management
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine Reuptake Inhibitors ... SerotoninNorepinephrine #Inhibitors ... #Pathophysiology ... #Pharmacology # ... Psychiatry #Diagnosis #Signs
Atopic Dermatitis - Topical Treatment Options 
First Line: Topical Corticosteroids 
  - High Potency: Betamethasone
After non-pharmacologic ... Remember that all ... a topical PDE4 inhibitor ... #Medications #Pharmacology ... #Dermatology #Management
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
: - Catch-all term ... - Pathophysiology ... red-flags to exclude dermatologic ... Ill-appearing, vital sign ... #Diagnosis #Dermatology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Aldosterone Release: ACE ... inhibitors, ARBs ... #Hyperkalemia #Pathophysiology ... #Pharmacology #
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
More Specific Signs ... endomyocardial biopsy Pharmacology ... : • ACE Inhibitors ... receptor-neprilysin inhibitors ... management #cardiology #pharmacology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... have fever - ACS ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... diagnosis #management #hematology
Drugs with Actions on Bronchial Smooth Muscle
Bronchodilation is promoted by cAMP. Intracellular levels of cAMP can
adenylyl cyclase (AC ... phosphodiesterase (PDE) inhibitors ... #SmoothMuscle #Pathophysiology ... #Pharmacology #