10 results
Gout Management in CKD
 • Colchicine
 • NSAID
 • Glucocorticoid
 • ACTH
 • Interleukin-1 Inhibitors

#Gout #Management
Gout Management ... in CKD • Colchicine ... #Management #CKD ... #rheumatology # ... treatment #comparison
Approach to Gout
Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals
Treatment:
 • Weight loss, diet, d/c culprit
medications • Acute ... • Colchicine: Acute ... and chronic treatment ... #diagnosis #management ... #rheumatology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
and Management ... gout treatment; ... Decrease dosage in CKD ... attack + stage ≥3 CKD ... #treatment #rheumatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... in those with CLD ... months without treatment ... #Chronic #Liver ... Failure #Cirrhosis #Hepatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
factors: Age>60, CKD ... At least 3 of (Acute ... , and CXR with pulmonary ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Gout - Management
Acute Gout Flare
 1) colchicine, NSAIDs, glucocorticoids
 2) Anakinra (IL-1 inhibitor)
When to Start Urate
Gout - Management ... Acute Gout Flare ... flare if sUA >9, CKD ... #Management #treatment ... #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Muscular: normal CK ... hepatitis • Pulmonary ... Disease #diagnosis #management ... #treatment #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... Eosinophilia, asthma, chronic ... Vessels: Supply gut ... • ANA (Suggest CTD ... #diagnosis #rheumatology
Management of Pruritus in Patients with Chronic Kidney Disease
Pruritus with no primary lesions - differential diagnosis:
Patients with Chronic ... primary lesions - differential ... pruritus • Hematologic ... #Pruritus #Treatment ... #Nephrology #CKD