12 results
Gout Management in CKD
 • Colchicine
 • NSAID
 • Glucocorticoid
 • ACTH
 • Interleukin-1 Inhibitors

#Gout #Management
Gout Management ... in CKD • Colchicine ... #Management #CKD ... #rheumatology # ... treatment #comparison
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
• IgG type ± C3d ... • Blood smear: Differential ... Anemia #diagnosis #management ... #treatment #rheumatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 33% • Treatment ... factors: Age>60, CKD ... , and CXR with pulmonary ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Muscular: normal CK ... hepatitis • Pulmonary ... Disease #diagnosis #management ... #treatment #rheumatology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
and Management ... Decrease dosage in CKD ... attack + stage ≥3 CKD ... #diagnosis #management ... #treatment #rheumatology
Gout - Management
Acute Gout Flare
 1) colchicine, NSAIDs, glucocorticoids
 2) Anakinra (IL-1 inhibitor)
When to Start Urate
Gout - Management ... Acute Gout Flare ... flare if sUA >9, CKD ... #Management #treatment ... #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... progressing GN • New pulmonary ... Vessels: Supply gut ... • ANA (Suggest CTD ... #diagnosis #rheumatology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
infection (IFI) in hematologic ... BAL GM does not differentiate ... SOT recipients, CGD ... or GVHD (leaky gut ... Galactomannan #diagnosis #comparison
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
both • Rule out ... Lymphadenitis, pulmonary ... Leishmaniasis Differential ... Inflammatory #Syndrome #Differential ... #Diagnosis #Management