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anemia differential causes cold workup agglutinin autoimmune classification disease enlarged hodgkins lymphoma macrocytic management microcytic oncology platelets spleen splenomegaly testing
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Lymphoproliferative disorder ... , Autoimmune disorder ... Mycoplasma, HIV, EBV ... #Anemia #hematology ... #diagnosis #comparison
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Algorithm Infectious ... Bacterial • Viral (EBV ... Myeloproliferative disorders ... Serum Sickness Hemolytic ... #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... workup, including BM ... blood loss, Acute hemolysis ... Inflammatory Conditions: Rheumatologic ... #Algorithm #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... Consider RBC membrane disorder ... #Algorithm #workup ... #hematology #testing
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... Diagnosis: • hemolytic ... - Mycoplasma, EBV ... #anemia #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... acute blood loss, hemolysis ... ) ablative disorders ... #Diagnosis #Workup ... #Hematology #Microcytic
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... replacing the BM ... replacing the BM-common ... #differential #diagnosis ... #causes #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... • Autoimmune disorders ... nodosum • Immune hemolytic ... lymph node biopsy (diagnostic ... classification #hematology
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