44 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
hematuria. ... RBC casts in urine ... Nephrotic #Syndromes #Classification ... #Proteinuria #Nephrology ... #Diagnosis
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... unilateral flank pain ... glomerular bleeding (proteinuria ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
and/or proteinuria ... (RBC casts or dysmorphic ... RBCs in urine)? ... Comparison #Algorithm #Nephrology ... #Diagnosis
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
- ++++ Hematuria ... - ++ Hematuria ... edgarvlermamd - Nephrology ... Comparison #Table #Nephrology ... #Diagnosis
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Diagnosis Framework ... → Diagnostic of ... Brown urine - Proteinuria ... #causes #urology ... #nephrology #renal
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... - Differential Diagnosis ... proliferative • Anti-GBM ... #Nephrology #Differential ... #Diagnosis #Algorithm
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
glomerular disease (hematuria ... , proteinuria) ... Glomerulonephritis #RPGN #Classification ... #Differential #Diagnosis ... #Nephrology
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
and Differential Diagnosis ... of Macroscopic Hematuria ... RBC’s, RBC/WBC casts ... , proteinuria suggest ... #EM #IM #Urology
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
eosinophiluria, microscopic hematuria ... , mild tubular proteinuria ... , granular casts ... #Algorithm #nephrology ... #diagnosis
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
presentation • Hematuria ... - 97% • Mean proteinuria ... /1.73 m2 at diagnosis ... • Dialysis at diagnosis ... Cryoglobulinemic #Nephrology