54 results
Glomerular Diseases - Spectrum
 - Insidious vs Acute
 - Nephritic (hypertension, hematuria, renal failure) vs Nephrotic
Glomerular Diseases ... - Insidious vs Acute ... (hypertension, hematuria ... Nephrotic (Heavy proteinuria ... differential #diagnosis #nephrology
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
repeat testing • Acute ... unilateral flank pain ... glomerular bleeding (proteinuria ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... syndrome—due to GBM ... hematuria. ... RBC casts in urine ... #Nephrology #Diagnosis
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Algorithmic Approach to Acute ... eosinophiluria, microscopic hematuria ... , mild tubular proteinuria ... MatthewHoMD #Acute ... #Algorithm #nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
basement membrane disease ... : • Flank pain ... Brown urine - Proteinuria ... of glomerular disease ... #urology #nephrology
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
the patient has hematuria ... and/or proteinuria ... (RBC casts or dysmorphic ... RBCs in urine)? ... Comparison #Algorithm #Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... proliferative • Anti-GBM ... Minimal change disease ... #Nephrology #Differential ... Diagnosis #Algorithm #Causes
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
RBC’s, RBC/WBC casts ... , proteinuria suggest ... intrinsic renal disease ... prostatic) #Diagnosis #EM ... #IM #Urology #Hematuria
Sickle Cell Disease (SCD) Nephropathy
 • Cortical Manifestations
    - Main issue: Hemolysis-associated endothelial
Sickle Cell Disease ... Manifestations - Main ... alterations - Proteinuria ... Manifestations - Hematuria ... #differential #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
of glomerular disease ... (hematuria, proteinuria ... proliferation in ... immune deposits in ... Differential #Diagnosis #Nephrology