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Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Systemic Lupus Erythematosus ... Renal #diseases #SLE ... #venn #nephrology ... #nephritis #classification ... #types #rheumatology
Lupus Classification
Spontaneous Lupus
 - Cutaneous Lupus Erythematosus (CLE)
 - Systemic Lupus Erythematosus 
Drug-Induced Lupus
 - Drug-Induced
Lupus Classification ... Lupus Erythematosus ... Lupusreference #Lupus #Classification ... #rheumatology # ... diagnosis #differential
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Systemic Lupus Erythematosus ... least 2 joints • Neurologic ... #Criteria #SLE ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... involvement 3% SLE-Related ... ) 30-45% Differential ... Lupusreference #SLE ... #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... (ACLE) • Erythematous ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... #Diagnosis #Rheumatology
Cutaneous Lupus Erythematosus
 • Acute Cutaneous Lupus (ACLE)
 • Neutrophilic Dermatoses 
 • Vascular Lesions
 •
Cutaneous Lupus Erythematosus ... Cutaneous Lupus (ACLE ... Cutaneous Lupus (SCLE ... #types #venn #rheumatology ... #classification
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... search ANA and aPL ... lupus #diagnosis #sle ... clues #system #erythematosus ... #rheumatology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Smith, Sm/RNP, Scl ... Scl100, Th/To, Scl ... body-like: - Neurologic ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS) - Differential ... Diagnosis Neurologic-Centered ... Features: POEMS, AL ... #Diagnosis #hematology ... #oncology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Systemic lupus erythematosus ... Screening Tests for All ... rubella titer, ACE ... diagnosis #testing #Rheumatology