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diagnosis hematology causes hyperkalemia management potassium erythematosus hodgkins lupus lymphoma monoclonal nephrology syndrome systemic ana antibody antinuclear apml arthritis behcet
Rheumatoid Arthritis - 2020 ACR-EULAR Classification ≥ 6 of 10 points = definite RA Joint Involvement:
Arthritis - 2020 ACR-EULAR ... Classification ... joint) - 5 points Serology ... - 2 points High ... #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... least 2 joints • Neurologic ... #EULARACR #Classification ... #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Smith, Sm/RNP, Scl ... Scl100, Th/To, Scl ... body-like: - Neurologic ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... test, ANA (e.g., SLE ... (CVID, WAS), (neurologic ... psychiatric changes), high ... not required in all
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS) - Differential ... Diagnosis Neurologic-Centered ... Features: POEMS, AL ... #Diagnosis #hematology ... #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
complements and a high ... Skin Disease Classification ... erythematosus (ACLE ... permanent alopecia Differential ... Non-autoimmune rheumatologic
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... phlebotomy High ... • NSAIDs • ACE ... insufficiency/Failure • SLE ... #nephrology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
translocation • Types: Classification ... involvement Differential ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... phlebotomy High ... • NSAIDs • ACE ... insufficiency/Failure • SLE ... #nephrology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... • Attempt if high ... initiation • Differential ... diagnosis #management #hematology ... #oncology
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