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diagnosis causes algorithm hypokalemia potassium management alkalosis syndrome workup gitelman low neurology rhabdomyolysis acidosis disorders high medications pharmacology renal summary
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Exogenous (KCL ... MunerMohamed1 #hyperkalemia ... #differential # ... diagnosis #pathophysiology
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Low intake • Metabolic ... Renal Losses: • Metabolic ... #Differential # ... potassium #low #nephrology
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... - Differential ... lysis syndrome • Metabolic ... blockers - MCW Nephrology ... #Differential #
Causes of Hypokalemia - Differential Diagnosis Algorithm Once pseudohypokalemia is ruled out, causes of hypokalemia can be
Causes of Hypokalemia ... - Differential ... that is leaky all ... #Differential # ... Causes #workup #nephrology
Hypokalemia Differential Diagnosis Algorithm Hypertensive: • High Al, Low R - Primary aldosteronism • High Al, High
Hypokalemia Differential ... Hypertensive: • High Al ... Gitelman's syndrome #Hypokalemia ... #Differential # ... Diagnosis #Algorithm #nephrology
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome Pathophysiology ... distal tubule. ↑ Nacl ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... #nephrology #diagnosis
Hypokalemia Differential Algorithm Acidosis - RTA - Diarrhea pH Normal 1. Decreased Mg 2. Intracellular Shift
Hypokalemia Differential ... Metabolic alkalosis ... NephTwitter) #Hypokalemia ... #Differential # ... Causes #Workup #Nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Non-anion Gap Metabolic ... ACE-Is and ARBs ... aniongap #NonGap #Metabolic ... #Acidosis #differential ... diagnosis #causes #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... • NSAIDs • ACE ... infusions) - Metabolic ... #differential # ... potassium #high #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm Hypovolemia, UNa > 20: • Renal losses, Diuretic excess,
Hyponatremia - Differential ... tubal acidosis and metabolic ... renal failure Hypervolemia ... #Hyponatremia #Differential ... Algorithm #Causes #nephrology
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