20 results
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... spontaneously (before any treatments ... malignancies Treatments ... #Tumor #Lysis #Syndrome ... #TLS #oncology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
malignancies Treatment ... Capillary leak syndrome ... • Tumor lysis syndrome ... #AKI #Cancer #Oncology ... Classification #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... distal tubule. ↑ Nacl ... #Pathophysiology ... #nephrology #diagnosis
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
in cardiorenal syndrome ... release • ↓ Cl ... #cardiorenal #syndrome ... #Mechanisms #pathophysiology ... #nephrology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... have fever - ACS ... organ damage • Treatment ... : • Pathophysiology ... Low calcium • Treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Triggers: ATRA treatment ... Pathophysiology ... management #hematology #oncology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Pathophysiology ... complete paralysis of all ... Treatment: • Plasmapheresis ... diagnosis #management #treatment ... #neurology
Pisa Syndrome (pleurothotonus) on Physical Exam
A tonic flexion of the trunk of the body to one
Pisa Syndrome (pleurothotonus ... Pathophysiology: ... Treatment: anticholinergics ... FatimahDandan #Pisa #Syndrome ... PhysicalExam #clinical #neurology
Tumor Lysis Syndrome (TLS) Pathophysiology
Culprits: ALL, Burkitt, SCLC
Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... (TLS) Pathophysiology ... #Tumor #Lysis #Syndrome ... #TLS #Pathophysiology ... #oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Puncture, EEG Treatment ... Erythematosus #SLE #CNS #neurology ... diagnosis #management #treatment