11 results
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Renal Potassium ... Aldosterone Release: ACE ... Pathophysiology #Pharmacology ... #Impaired #Potassium
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• NSAIDs • ACE ... • Recent IV potassium ... Beta blockers • Antibiotics ... resistance Impaired ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• NSAIDs • ACE ... • Recent IV potassium ... Beta blockers • Antibiotics ... resistance Impaired ... #high #nephrology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Cardiac failure: Impaired ... thromboembolism, renal ... tumors INTRINSINC RENAL ... NSAlDs, antibiotics ... Differential #Diagnosis #nephrology
Management of Pediatric Kidney Stones
Acute Managment:
 • Pain relief: NSAIDs, opioids
 • Facilitating passage of stone:
Recurrence: • For ALL ... Monitoring for extra-renal ... alkalinisation: potassium ... alkalinization: potassium ... Management #Pediatrics #nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
oxoproline) • Renal ... Renal acidosis ... Potassium-sparing ... ACE-Is and ARBs ... diagnosis #causes #nephrology
Effects of Prostaglandins and NSAIDs on the Kidney
Effects of Prostaglandins on the Kidney:
 • The vasodilatory
importance in renal ... production of renal ... hormones that act ... NSAIDs #Kidney #renal ... #nephrology #pharmacology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... • Inhibit Na+ Cl ... Piretanide Potassium ... #Diuretics #Pharmacology ... #nephrology #conversion
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
130 mEq/L • Potassium ... filtration - Renal ... blood flow and renal ... clotting factors - impair ... NS #comparison #pharmacology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
NSAIDs, β-blockers, Antibiotics ... 15 suggests ↓ renal ... Ca-gluconate or 1g CaCl ... Management #Treatment #potassium ... #nephrology #K