21 results
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Potassium Excretion ... Aldosterone Release: ACE ... Decreased Na, K-ATPase ... Pathophysiology #Pharmacology ... #Renal
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
- Differential Diagnosis ... • NSAIDs • ACE ... Beta blockers • Antibiotics ... #causes #potassium ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
- Differential Diagnosis ... • NSAIDs • ACE ... • Recent IV potassium ... Beta blockers • Antibiotics ... #high #nephrology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
- Differential Diagnosis ... Losses Non-renal ... vomiting) • Low K ... #Algorithm #nephrology ... #low #potassium
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Increased EC shift of K ... • Exogenous (KCL ... #differential #diagnosis ... pathophysiology #pharmacology ... #potassium #medications
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
- Differential Diagnosis ... loss • Renal ... hypokalemia • Renal ... algorithm #causes #nephrology ... #potassium
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... suggests extra-renal ... #Hypokalemia #diagnosis ... #differential #potassium ... #nephrology #low
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
the basis of the potassium-to-creatinine ... • Low Urine Cl ... hypokalemia #urine #potassium ... differential #algorithm #diagnosis ... #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Epithelial Cells Renal ... syndrome - Na-K- ... , K channel, Cl ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... NSAIDs, β-blockers, Antibiotics ... Ca-gluconate or 1g CaCl ... Management #Treatment #potassium ... #nephrology #K