21 results
diagnosis differential causes nephrology management tls oncology potassium high pathophysiology algorithm cancer classification hypermagnesemia hyperphosphatemia hypokalemia rhabdomyolysis tumorlysis uricacid workup
Pathophysiology of Tumor Lysis Syndrome (TLS) Tumor Cell Lysis -> Release of DNA • Purines -> Hypoxanthine /
Pathophysiology of Tumor ... Lysis Syndrome ... (TLS) Tumor Cell ... Lysis -> Release ... Hypocalcemia • Hyperkalemia
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Lysis Syndrome ... organ damage • Treatment ... Lysis Syndrome: ... hydration - Hyperkalemia ... #Lysis #Syndrome
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... malignancies Treatments ... 6L/day) • For hyperkalemia ... wandering_er #Tumor ... #Lysis #Syndrome
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Cancer Related • Hypercalcemia ... nephropathy • Solid tumors ... malignancies Treatment ... Interleukin-2) • Tumor ... lysis syndrome
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Intracellular Shift ... release due to cell lysis ... Transfusion reaction - Tumor ... lysis syndrome
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
Classification of Tumor ... Lysis Syndrome ... (TLS) and Treatment ... hydroxide • Hyperkalemia ... #TumorLysis #Syndrome
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... Intercellular Shift ... Transcellular Shift ... Tumor Lysis Syndrome ... • Digoxin #Hyperkalemia
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Intracellular Shift ... release due to cell lysis ... Transfusion reaction - Tumor ... lysis syndrome
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... Rhabdomyolysis • Tumor ... lysis syndrome ... MCW_Nephrology #HyperKalemia
Causes of Hypermagnesemia Increased magnesium load - Magnesium-containing laxatives, antacids, or enemas - Treatment of pre-edampsia/eclampsia (mothers
or enemas - Treatment ... untreated) - Tumor ... lysis - Rhabdomyolysis ... hypocalciuric hypercalcemia
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