43 results
Oxygen-Hemoglobin Dissociation Curve

Left Shift (↓ O2 unloading to tissue), Left = Lower:
 • ↓ H+ (↑
Oxygen-Hemoglobin Dissociation ... Curve Left Shift ... Temperature Right Shift ... Oxygen #Hemoglobin #Dissociation ... #Curve #pathophysiology
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
Oxyhemoglobin Dissociation ... Curve Left Shift ... Oxyhemoglobin #Dissociation ... #Curve #Pathophysiology ... Differential #Causes #Diagnosis
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
- Differential Diagnosis ... Transcellular Shift ... #Differential #Diagnosis ... Algorithm #causes #potassium ... #low #pathophysiology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
- Differential Diagnosis ... Transcellular Shift ... Transcellular shifts ... #Differential #Diagnosis ... nephrology #low #potassium
Causes of Hyperkalemia - Differential Diagnosis Algorithm
 • Increased Intake
 • Reduced Excretion (IV potassium with
- Differential Diagnosis ... Excretion (IV potassium ... Transcellular Shift ... #Differential #Diagnosis
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... #differential #diagnosis ... #pathophysiology ... #pharmacology #potassium
Causes of Hyperkalemia

Hyperkalemia is caused by excess potassium intake, impaired potassium excretion, or transcellular shifts. The
caused by excess potassium ... intake, impaired potassium ... transcellular shifts ... adapt to excess potassium ... dysfunction is common #Diagnosis
Pathophysiology Of Constriction
Exaggerated Ventricular Interdependence:
 • Limited Cardiac Filling due to Fixed Volume → Septum Shifts
Pathophysiology ... Volume → Septum Shifts ... Intrathoracic-lntracardiac Dissociation ... #pericarditis #pathophysiology ... #cardiology #dissociation
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Dialysis Serum potassium ... blocks, QRS axis shift ... #hyperkalemia #potassium ... #high #diagnosis
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
Anterior Shoulder Dislocation ... Anterior Shoulder Dislocation ... x-ray view -> Dislocation ... #Diagnosis #signs ... #orthopedics #pathophysiology