58 results
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
manifestations of Down syndrome ... • Brushfield spots ... iris (pigmented spots ... #Downs #Syndrome ... PhysicalExam #Features #Signs
Rheumatoid Arthritis Summary
MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
PIP Involvement, Spares ... Tunnel, Sicca Syndrome ... Scleritis, Heart Disease ... Nodules, Pulmonary Disease ... #rheumatology #signs
Risk Factors and Signs of Copper Deficiency
Risk Factors:
 • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Risk Factors and Signs ... Chronic diarrhoea, Short ... bowel syndrome, ... dental fixatives, Treatment ... , Malnutrition Signs
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
LC deposition disease ... Minimal change disease ... malignancies Treatment ... Capillary leak syndrome ... #AKI #Cancer #Oncology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... with systemic diseases ... erythematosus (SLE) Signs ... #Pathophysiology ... #Diagnosis #Signs
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Short Stature - ... • Turner Syndrome ... • Cushing's Disease ... Panhypopituitarism Treatment ... Transplant Chronic Disease
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... =>Prader-Willi Syndrome ... Signs/Symptoms ... fractures • Short ... #genetics #pathophysiology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
with more severe disease ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Treatment: • ... Hydroxychloroquine *Short
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... organ damage • Treatment ... : • Pathophysiology ... Low calcium • Treatment
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... mutations - Down syndrome ... chromosome 21) Signs ... AlzheimersDisease #Dementia #pathophysiology ... geriatrics #diagnosis #signs