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diagnosis differential dermatology management sle symptoms erythematosus systemic algorithm arthritis vasculitis blood classification comparison dermatomyositis druginduced joint msk pain pathophysiology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Skin Conditions ... B19 infection Malar ... lesions • Discoid lupus ... Sarcoidosis #dermatology ... differential #diagnosis #rheumatology
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis Malar rash: • A
Combination of Skin ... Differential Diagnosis Malar ... Suggestive of: Lupus ... migrans: • Target sign ... gabrieltalledop #dermatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Arthritis 69% - Malar ... Diagnosis and Lupus ... autoantibodies #signs ... #differential #rheumatology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
SLE) - Typical Signs ... Alopecia, Fever, Malar ... Adenopathies, Lupus ... Erythematosus #SLE #Signs ... Symptoms #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar ... , oral ulcers, Lupus ... Positive in 60-80% of cases ... Management #Summary #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Sjögrens (15%) Skin ... Thrombocytopenia #Lupus ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... usually IgG) (e.g. lupus ... • Infections: Malaria ... Extravascular #Causes ... differential #diagnosis #hematology
Physiologic Skin Changes in Pregnancy - Differential Diagnosis Algorithm Face • Melasma Abdomen • Linea Nigra Hormone induced
Physiologic Skin ... • Chadwick's sign ... Hyperhidrosis • Miliaria ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
cases, drug-dependent ... & NPSLE rare, Malar ... Discontinuation of causal ... Manifestations: Malar ... comparison #table #rheumatology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... inflammation on skin ... -> Malar (butterfly ... pathophysiology #diagnosis #signs
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