202 results
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Thrombocytopenic Purpura ... children) • Platelets ... extremely low platelet ... Thrombocytopenic #Purpura
Indications for Transfusion
Packed RBCs
 • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
thrombocytopenic thrombotic purpura ... Platelet transfusions ... thrombocytopenic purpura ... posttransfusion purpura ... thrombocytopenic purpura
Causes of Purpura - Differential Diagnosis
Disruption in Vascular Integrity: 
 • Trauma, Infection, Vasculitis, Drug induced
Causes of Purpura ... C), Pigmented purpuric ... Thrombocytopenia, Platelet ... BrighamChiefs #Purpura
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... RBC's secondary to platelet ... Thrombocytopenia • Platelet ... OF NON-PALPABLE PURPURA ... : Platelet Defects
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
Causes of Purpura ... in Children Platelet ... thrombocytopenic purpura ... Henoch—Schönlein purpura ... - Scurvy #Purpura
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Thrombocytopenic Purpura ... secondary TMA), Platelets ... Contraindication to platelets ... Thrombocytopenic #Purpura
Algorithm for the outpatient management of thrombocytopenia. 
(DIC = disseminated intravascular coagulation; EDTA = ethylenediaminetetraacetic acid;
enzymes, and low platelet ... thrombocytopenic purpura ... thrombocytopenic purpura
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
Rash - Palpable Purpura ... Purpura: Low Platelets ... with lower leg purpura ... Palpable purpura ... vs Vasculitis purpura
Bleeding manifestations 
Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
areas of the body Purpura ... Purpura due to vasculitis ... Wet purpura is the ... lowest levels Platelet ... ability to bind platelets
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Petechiae • Purpura ... Hemorrhagic bullae • Purpura ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet