661 results
Indications for Transfusion
Packed RBCs
 • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
Indications for Transfusion ... • < 30,000 and bleeding ... postoperative bleeding ... Platelet transfusions ... Willebrand disease #Transfusion
Thresholds for Transfusion of Platelets in Adults
Major surgery or invasive procedure, no active bleeding - 
≤
Thresholds for Transfusion ... of Platelets in ... procedure, no active bleeding ... #Management #Platelets ... #Transfusion #Plateletpheresis
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
donor (apheresis) platelets ... , due to anti-platelet ... common following platelet ... coagulopathy & ↑bleeding ... contamination: Platelets
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
, due to anti-platelet ... Injury (TRALI): Leading ... common following platelet ... coagulopathy & ↑bleeding ... contamination: Platelets
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Findings: • Bleeding ... incompatible blood transfusion ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... hydration • RBC transfusion
Procedure Risks and Platelet Targets for Transfusion
LOW RISK - Transfuse ≥ 20,000/uL
 • Paracentesis, EGD or
Procedure Risks and Platelet ... Targets for Transfusion ... Prophylactic variceal bleeding ... Aguila @enrrikke #Platelet ... #Transfusion #thresholds
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
neutropenia • Mucosal bleeding ... from low platelets ... Supportive care (transfusions
Acute Non-Variceal Upper GI Bleeding
Pre-Endoscopy Management:
 • Hemodynamic resuscitation
 • No routine NG tube
 • Risk
Non-Variceal Upper GI Bleeding ... Restrictive blood transfusion ... management — anti-platelet ... If peptic ulcer bleeding
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Menorrhagia • GI bleeding ... children) • Platelets ... only for severe bleeding ... extremely low platelet
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Evidence Summary for Transfusion ... show that PRBC transfusions ... Unnecessary transfusions ... Transfusions should ... Transfusions are