28 results
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... cascade is shown ... #Coagulation #Cascade ... #platelet #thrombin ... PTT #diagnosis #models
Hemostasis Physiology

The blood's response to blood vessel injury can be viewed as four interrelated steps. 
Roman
numerals refer to coagulation ... diphosphate; PF-3, platelet ... Pathophysiology #Coagulation ... #Cascade #Hematology
Review of the Coagulation Cascade
Traditional Model:
 • Parallel extrinsic and intrinsic pathways.
Contemporary Model:
 • 4 key
Review of the Coagulation ... Cascade Traditional ... Initiation phase caused ... , resulting in coagulation ... #Cascade #diagnosis
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Sequestration Disordered Platelet ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Bleeding and Bruising - Differential Diagnosis Algorithm
 • Vascular System Defect - Congenital vs Acquired
 •
Differential Diagnosis Algorithm ... vs Acquired • Platelet ... Qualitative • Coagulation ... Differential #Diagnosis #Algorithm
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
RBC's secondary to platelet ... vascular disorders, coagulation ... Thrombocytopenia • Platelet ... defects • Coagulation ... NON-PALPABLE PURPURA: Platelet
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... Treat primary cause ... #diagnosis #causes
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged ... Differential #Diagnosis #Algorithm ... #Causes #Hematology ... #coagulation #disorders
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
presents with coagulation ... Liver tests, Low Platelets ... child * Severe cases ... pregnancy * Severe coagulation
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
presents with coagulation ... Liver tests, Low Platelets ... child * Severe cases ... pregnancy * Severe coagulation