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Diagram demonstrating TEG (thromboelastography) variables as they relate to the coagulation cascade.

Dr. Wells Brambl @DoctorWellsMD

#TEG #thromboelastography
demonstrating TEG ... relate to the coagulation ... cascade. ... DoctorWellsMD #TEG ... #cascade #anticoagulation
Hemostasis Physiology

The blood's response to blood vessel injury can be viewed as four interrelated steps. 
Roman
numerals refer to coagulation ... diphosphate; PF-3, platelet ... Pathophysiology #Coagulation ... #Cascade #Hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... cascade is shown ... multicomponent complexes on platelets ... #Coagulation #Cascade ... #platelet #thrombin
Thromboelastogram Interpretation
Reaction Time (R Value):
 - Time till initiation of fibrin clot
 - Treatment: FFP, protamine
K
representing thrombin-platelet ... - Treatment: Platelets ... Thromboelastogram #TEG ... Thromboelastography #diagnosis #coagulation
Bleeding and Bruising - Differential Diagnosis Algorithm
 • Vascular System Defect - Congenital vs Acquired
 •
Differential Diagnosis Algorithm ... vs Acquired • Platelet ... Qualitative • Coagulation ... Differential #Diagnosis #Algorithm
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct 60% Platelet ... pheresis - Platelets ... proteins, all coagulation ... Hematology #Management #Table
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Differential Diagnosis Algorithm ... Sequestration Disordered Platelet ... • Vasculitis Coagulation ... deficiencies Coagulation ... Differential #Diagnosis #Algorithm
THROMBOELASTOGRAPHY (TEG)
General Principle
• A small cuvette is rotated to simulate sluggish venous flow and stimulate clot
THROMBOELASTOGRAPHY (TEG ... problems with coagulation ... cascade and platelet ... @nickmmark #TEG
Thromboelastography (trademarked as TEG)
 • Graphical representation of the fibrin polymerization process
 • Point-of-care anti-coagulation monitoring
trademarked as TEG ... Point-of-care anti-coagulation ... routine transfusion algorithms ... deficiency → give platelets ... Thromboelastogram #TEG
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
presents with coagulation ... Liver tests, Low Platelets ... pregnancy * Severe coagulation ... Diagnosis #Comparison #Table