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diagnosis hematology differential management thrombocytopenia bruising pathophysiology teg thromboelastography bleeding interpretation obstetrics purpura aflp anticoagulation comparison dermatology hellp hemostasis models
Diagram demonstrating TEG (thromboelastography) variables as they relate to the coagulation cascade. Dr. Wells Brambl @DoctorWellsMD #TEG #thromboelastography
relate to the coagulation ... cascade. ... thromboelastography #thromboelastogram ... #coagulation #cascade
Thromboelastogram Interpretation Reaction Time (R Value): - Time till initiation of fibrin clot - Treatment: FFP, protamine K
Thromboelastogram ... representing thrombin-platelet ... - Treatment: Platelets ... rishikumarmd #Thromboelastogram ... Thromboelastography #diagnosis #coagulation
Hemostasis Physiology The blood's response to blood vessel injury can be viewed as four interrelated steps. Roman
numerals refer to coagulation ... diphosphate; PF-3, platelet ... Pathophysiology #Coagulation ... #Cascade #Hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... cascade is shown ... multicomponent complexes on platelets ... #Coagulation #Cascade ... #platelet #thrombin
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Sequestration Disordered Platelet ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Bleeding and Bruising - Differential Diagnosis Algorithm • Vascular System Defect - Congenital vs Acquired •
Differential Diagnosis Algorithm ... vs Acquired • Platelet ... Qualitative • Coagulation ... Differential #Diagnosis #Algorithm
THROMBOELASTOGRAPHY (TEG) General Principle • A small cuvette is rotated to simulate sluggish venous flow and stimulate clot
problems with coagulation ... cascade and platelet ... nickmmark #TEG #Thromboelastogram
Thromboelastography (trademarked as TEG) • Graphical representation of the fibrin polymerization process • Point-of-care anti-coagulation monitoring
Point-of-care anti-coagulation ... routine transfusion algorithms ... amplitude • If ↓ → platelet ... deficiency → give platelets ... Thromboelastography #Thromboelastogram
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
RBC's secondary to platelet ... vascular disorders, coagulation ... Thrombocytopenia • Platelet ... defects • Coagulation ... NON-PALPABLE PURPURA: Platelet
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... Treat primary cause ... #diagnosis #causes
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