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diagnosis hematology bleeding causes interpretation petechiae purpura teg thrombocytopenia thromboelastography blanching bruise criticalcare dermatology ecchymosis hematomas hemostasis leukemoid leukocytosis management
Bleeding and Bruising - Differential Diagnosis Algorithm • Vascular System Defect - Congenital vs Acquired •
Bleeding and Bruising ... - Differential ... Diagnosis Algorithm ... vs Acquired • Platelet ... Qualitative • Coagulation
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
of Bleeding / Bruising ... - Differential ... Diagnosis Algorithm ... Sequestration Disordered Platelet ... #Differential #
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... Diagnosis Algorithm ... Symptoms: B-symptoms, bruising ... anemia, ↑ MCV, ↑/↓ platelets ... #Diagnosis #Algorithm
THROMBOELASTOGRAPHY (TEG) General Principle • A small cuvette is rotated to simulate sluggish venous flow and stimulate clot
problems with coagulation ... cascade and platelet ... nickmmark #TEG #Thromboelastogram
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... of Hemostasis - Differential ... Qualitative defect in platelets ... characteristic of a platelet ... integrity Clotting cascade
Thromboelastography (trademarked as TEG) • Graphical representation of the fibrin polymerization process • Point-of-care anti-coagulation monitoring
Point-of-care anti-coagulation ... routine transfusion algorithms ... amplitude • If ↓ → platelet ... deficiency → give platelets ... Thromboelastography #Thromboelastogram
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
are typical of coagulation ... Excessive bruising ... lowest levels Platelet ... ability to bind platelets ... VWF:RCo/VWF:Ag (differentiate
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Purpura or Easy Bruising ... in Children Platelet ... intravascular coagulation ... Scurvy #Purpura #Bruising ... pediatrics #diagnosis #differential
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Diagnosis Algorithm ... Thrombocytopenia - Abnormal platelet ... Complete blood count coagulation ... #Diagnosis #Algorithm
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