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diagnosis differential hematology thrombocytopenia dermatology management oncology pediatrics peds petechiae purpura accessories atlas basics blanching bruise child colonoscopy devices dic
Bleeding and Bruising - Differential Diagnosis Algorithm • Vascular System Defect - Congenital vs Acquired •
Bleeding and Bruising ... vs Acquired • Platelet ... Qualitative • Coagulation ... vs Acquired #Bleeding ... #Diagnosis #Algorithm
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm ... Sequestration Disordered Platelet ... #Bleeding #Bruising
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Differential Diagnosis Algorithm ... Symptoms: B-symptoms, bruising ... /bleeding, fatigue ... anemia, ↑ MCV, ↑/↓ platelets ... Differential #Diagnosis #Algorithm
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... Treat primary cause ... #diagnosis #causes
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... PT (INR) - No Bleeding ... Differential #Diagnosis #Algorithm ... #Causes #Hematology ... #coagulation #disorders
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
ecchymosis) is caused ... are typical of coagulation ... Excessive bruising ... lowest levels Platelet ... ability to bind platelets
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... Qualitative defect in platelets ... characteristic of a platelet ... inhibitor of a coagulation ... discern these causes
Thromboelastography (trademarked as TEG) • Graphical representation of the fibrin polymerization process • Point-of-care anti-coagulation monitoring
trademarked as TEG ... Point-of-care anti-coagulation ... routine transfusion algorithms ... deficiency → give platelets ... Thromboelastogram #TEG
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... or Easy Bruising ... intravascular coagulation ... Scurvy #Purpura #Bruising ... #Causes #peds #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Easy or unusual bruising ... or bleeding, which ... by bleeding (petechiae ... Out Secondary Causes
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