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diagnosis hematology differential management thrombocytopenia causes bruising purpura treatment aflp anticoagulation dermatology hellp hemolytic obstetrics pediatrics peds petechiae pregnancy risk
Bleeding and Bruising - Differential Diagnosis Algorithm • Vascular System Defect - Congenital vs Acquired •
Bleeding and Bruising ... Differential Diagnosis Algorithm ... vs Acquired • Platelet ... Qualitative • Coagulation ... vs Acquired #Bleeding
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Sequestration Disordered Platelet ... #Bleeding #Bruising ... Differential #Diagnosis #Algorithm
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Differential Diagnosis Algorithm ... B-symptoms, bruising/bleeding ... hepatomegaly • Labs: anemia ... , ↑ MCV, ↑/↓ platelets ... Differential #Diagnosis #Algorithm
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... Findings: • Bleeding ... Findings: • Bleeding ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... Differential Diagnosis Algorithm ... hemolysis, deficiency anemia ... Thrombocytosis #Platelets ... Differential #Diagnosis #Algorithm
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... Microangiopathic hemolytic anemia ... intravascular coagulation ... other testing (platelet ... microangiopathic #hemolytic #anemia
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
Bleeding manifestations ... are typical of coagulation ... lowest levels Platelet ... ability to bind platelets ... Measurement of coagulation
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
RBC's secondary to platelet ... Thrombocytopenia • Platelet ... defects • Coagulation ... NON-PALPABLE PURPURA: Platelet ... - Hemolytic anemia
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... neutropenia • Mucosal bleeding ... from low platelets ... • Symptomatic anemia ... megaloblastic anemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Thrombocytopenia and Platelet ... History: - Prior platelet ... - History of bleeding ... changes), high MCV anemia ... Thrombocytopenia #Platelet
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