21 results
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... count and platelet ... (either severe Type ... 1 or Type 3) — ... considered first-line testing
Bleeding and Bruising - Differential Diagnosis Algorithm
 • Vascular System Defect - Congenital vs Acquired
 •
Bleeding and Bruising ... Differential Diagnosis Algorithm ... vs Acquired • Platelet ... #Bleeding #Bruising ... Differential #Diagnosis #Algorithm
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Differential Diagnosis Algorithm ... Symptoms: B-symptoms, bruising ... anemia, ↑ MCV, ↑/↓ platelets ... Differential #Diagnosis #Algorithm
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... Differential Diagnosis Algorithm ... hematology for workup ... Thrombocytosis #Platelets ... Differential #Diagnosis #Algorithm
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
of Bleeding / Bruising ... Differential Diagnosis Algorithm ... Sequestration Disordered Platelet ... #Bleeding #Bruising ... Differential #Diagnosis #Algorithm
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
Differential Diagnosis Algorithm ... < 1800/uL, • platelet ... /uL Initial Workup ... Differential #Diagnosis #Algorithm ... #hematology #workup
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Clinical • Easy bruising ... Laboratory • Normal platelet ... thrombocytopenia in type
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Thrombocytopenia and Platelet ... Diagnosis and Workup ... History: - Prior platelet ... smear, HIV/HCV testing ... Thrombocytopenia #Platelet
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
to a low blood platelet ... neutrophils and platelets ... Neutropenia • Platelet ... blood cells or platelets ... blood cells or platelets
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... with or without platelet ... Differential #Diagnosis #Algorithm ... #workup #hematology ... #testing