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diagnosis hematology differential management anemia acute allergy blood hypersensitivity nephrology physicalexam product treatment types aki allergic approach atlas beaus bleeding
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
donor (apheresis) platelets ... Transfusion Reactions ... Causes purpura & ... TRALI): Leading cause ... more likely to cause
Hemolysis Classification - Intrinsic and Extrinsic Causes Commentary: Another way to think of immune hemolysis would be
Hemolysis Classification ... hemolysis, hemolytic transfusion ... reactions) - Dr ... #Hemolysis #Classification ... #Algorithm
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
, due to anti-platelet ... Causes purpura & ... TRALI): Leading cause ... common following platelet ... more likely to cause
Thromboelastography (trademarked as TEG) • Graphical representation of the fibrin polymerization process • Point-of-care anti-coagulation monitoring
determining if transfusion ... algorithms and ... patients) R (reaction ... amplitude • If ↓ → platelet ... deficiency → give platelets
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Anemia Intrinsic Causes ... Intravascular Causes ... prosthetic valve • Transfusion ... reactions ex. ... #classification
Causes of Acute Onset Fever - Differential Diagnosis Algorithm Viral: • Rhinovirus • Influenza Virus • Parainfluenza
Causes of Acute ... Differential Diagnosis Algorithm ... Iatrogenic: • Transfusion ... reaction • Malignant ... #causes
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
hypersensitivity reactions ... Allergen-specific lgE causes ... Examples: Acute transfusion ... reaction, Haemolytic ... allergy #table #classification
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Destruction • Abnormal ... Sequestration Disordered Platelet ... #Causes #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
incompatible blood transfusion ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... Treat primary cause ... hydration • RBC transfusion
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... osmolarity If cause ... investigations abnormal ... fragmentocytes, LDH, platelets ... #AKI #Workup #Algorithm
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