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diagnosis syndrome hematology neurology differential oncology cardiology endocarditis guillain abscess activation acute aiha aplastic arteritis autoimmune capillary cerebritis clarksons classification
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... response preceding infection ... Treatment: • Plasmapheresis ... Syndrome #diagnosis #management ... #treatment #neurology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... risk-stratification • Risks: infection ... only curative treatment ... #treatment #hematology
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Autoimmune Hemolytic Anemia ... (AIHA) Treatment ... Steroids - 1-2 mg/kg ... Polyclonal: - Infection ... #management #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... Idiopathic • Infections ... CMV) • Epstein-Barr ... Treatment: ... #diagnosis #management
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... and cauda equina TREATMENT ... Syndrome #diagnosis #management ... #neurology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
autoimmune hemolytic anemia ... and M panel Management ... DDX - Other causes ... (Epstein-Barr syndrome ... #diagnosis #management
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... • Most common cause ... 38 degrees • Chills ... Leukocytosis, anemia ... #management #treatment
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... Lumbar Puncture, EEG ... #rheumatology # ... cerebritis #diagnosis #management ... #treatment
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
loss (>5 lb; 2.5 kg ... 14%), in which case ... enzymes ↑ • Mild anemia ... DDX: • Epstein-Barr ... antibody test) Treatment
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Diagnosis Neonate: - Infection ... hypertension and/or drug treatment ... Constitutional disorders, eg ... Megaloblastic anemia-rare ... #hematology
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