10 results
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Volume (MCV) - Differential ... • Marrow Aplasia ... , Target Cells ... #Differential #
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute leukemia ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... aplasia • ITP ... microglobulin Treatment ... leukemia #CLL ... diagnosis #workup #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
mass • Rapidly rising ... -> AML: Blast crises ... PLT: Petechiae, bruising ... - infiltrates (anemia ... #Hematology #Oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... and petechiae Causes ... anemia Treatment ... #Anemia #oncology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
- Differential ... Megakaryopoiesis • Aplastic ... Anemia • Toxic ... Leukemia, Tumour ... ITP • SLE • CLL
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Easy or unusual bruising ... • AnemiaAplastic ... Leukemia • Idiopathic ... blood count with differential ... diagnosis #hematology #oncology
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
Causes of Purpura ... or Easy Bruising ... Acquired - Aplastic ... infiltration (e.g. leukaemia ... pediatrics #diagnosis #differential
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... classification #hematology #oncology
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
- Differential ... hypertension and/or drug treatment ... Megaloblastic anemia-rare ... including white blood cell ... aplasia DOI: 10.1111