63 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... Diagnosis and Treatment ... #HES #Hematology ... eosinophils #diagnosis #management ... #algorithm
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
autoantibodies: positive ... • Blood smear: Differential ... → schizocytes, Positive ... Anemia #diagnosis #management ... #treatment #rheumatology
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Antisynthetase Syndrome ... Myopathy #Comparison #Managment ... #algorithm #Rheumatology ... #Differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #Diagnosis #Algorithm
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... refractory lesions Ocular ... Behcets #disease #Syndrome ... #Treatment #management ... #pharmacology #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Skin lesions • Positive ... Behcet disease) Differential ... Arthritis, AS Treatment ... #diagnosis #management ... signs #symptoms #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... 40, F:M 9:1 • Clinical ... - Anti-dsDNA - Positive ... life-threatening • Treatment ... #Summary #rheumatology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... vonWillebrand #Syndrome ... #treatment #hematology ... #differential
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... • Ocular: uveitis ... Disease #diagnosis #management ... #treatment #rheumatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... Diagnosis Algorithm ... Responsive to Treatment ... pathophysiology #Hematology ... #algorithm