42 results
Renal Involvement in Systemic Lupus Erythematosus

Dr. Laurent ARNAUD @Lupusreference

#Renal #diseases #SLE #Systemic #Lupus #Erythematosus #venn #nephrology
Involvement in Systemic Lupus ... Lupusreference #Renal #diseases ... SLE #Systemic #Lupus ... Erythematosus #venn #nephrology ... classification #types #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
Diagnostic Algorithm for Dizziness and Vertigo
Peripheral Vertigo:
 • Attacks: Sudden, severe, can last anywhere from seconds
Varies • No neurologic ... change • Neurologic ... auditory findings BPPV ... test Méniére's disease ... differential #diagnosis #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... Puncture, EEG Treatment ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... diagnosis #management #treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Anti-histone - Positive ... constitutional symptoms • Treatment ... life-threatening • Treatment ... Evolution: Chronic disease ... comparison #table #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... , Drug-induced Lupus ... Speckled: Systemic lupus ... , Drug-Induced Lupus ... ANA #patterns #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
Criteria - Systemic Lupus ... ACUTE CUTANEOUS LUPUS ... SEROSITIS - RENAL - NEUROLOGIC ... determined by Positive ... #Diagnosis #Rheumatology
Characteristics of Peripheral and Central Vertigo
PERIPHERAL VERTIGO
 • Onset: Sudden
 • Intensity: Severe initially, often decreasing
labyrinthitis • Head Position ... tinnitus (Méniére's disease ... nose) • Head Position ... worsen with head position ... symptoms #comparison #neurology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... with more severe disease ... Treatment: • ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... pain (20%) Renal disease ... haemolytic Coombs positive ... Thrombocytopenia #Lupus ... symptoms #diagnosis #rheumatology