28 results
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
only covers Gram positives ... skin/soft tissue infections ... MRSA bacteremia/endocarditis ... cidal nature) #Pharmacology ... #Antibiotics #Review
Vancomycin and Dalbavancin (lipoglycopeptide antibiotics) - Antibiotics Class Overview

Mechanism: Glycopeptide -  inhibits cell wall synthesis
standard for MRSA infections ... infections from ... infections in patients ... #Pharmacology #Antibiotics ... #Review #Overview
Aminoglycosides  - Antibiotics Class Overview

Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV)
Spectrum: Extremely efficacious vs.
gram negative infections ... urinary tract infections ... effect (mainly in endocarditis ... #Pharmacology #Antibiotics ... #Review #Overview
IDSA Treatment of Necrotizing Infections of the Skin, Fascia, and Muscle
 • Mixed infections
 • Streptococcus
Necrotizing Infections ... Muscle • Mixed infections ... #Necrotizing #Infections ... #Treatment #management ... #antibiotics #pharmacology
Table of Antibiotics for Highly Resistant Gram Positive Infections 

- Dr. Eric Strong @DrEricStrong - Strong
Resistant Gram Positive ... Infections - ... #GramPositive #Infections ... #Table #Pharmacology ... #Coverage #Management
Carbapenems - Antibiotics Class Overview

Imipenem/Cilastin, Meropenem, Ertapenem, Doripenem 

Spectrum: Broadest spectrum antibiotics, cover Gram positive, Gram
, cover Gram positive ... : many serious infections ... intraabdominal infections ... and soft tissue infections ... #Antibiotics #Review
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
severe fungal infections ... severe candidal infections ... (endocarditis, ... urinary tract infections ... #Pharmacology #Antibiotics
Tigecycline (IV) - Antibiotics Class Overview

Mechanism: Glycylcycline class - structurally related to Tetracyclines (bacteriostatic).  Only
coverage - Gram positive ... intraabdominal infections ... skin/soft tissue infections ... #Pharmacology #Antibiotics ... #Review #Overview
Antifungal Polyenes - Amphoterecin B, Abelcet, Ambisome - Antibiotics Class Overview

Mechanism: binds ergosterol in membrane and
forms membrane pores ... severe fungal infections ... 2nd-line for candida infections ... #Pharmacology #Antibiotics ... #Review #Overview
Linezolid (Zyvox) (PO and IV) - Antibiotics Class Overview

Mechanism: Oxazolidinone class –unique ribosomal inhibitor (acts on
covers all Gram positives ... skin/soft titssue infections ... suspected MRSA, VRE infections ... #Pharmacology ... #Antibiotics #Review