114 results
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
in cardiorenal syndrome ... • Increased renal ... hypertrophy • Sodium ... #cardiorenal #syndrome ... pathophysiology #nephrology
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential Diagnosis ... Osmolarity 3) Urine Sodium ... High Uric Acid → renal ... #Algorithm #nephrology ... #sodium #low #uricacid
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... Repeat the sodium ... • nephrotic syndrome ... Hypernatremia #Diagnosis ... Workup #Algorithm #Nephrology
General approach to AKI - Checklist

Urine electrolytes & FENa - Previously, it was believed that urine
believed that urine sodium ... fractional excretion of sodium ... and intrinsic renal ... performance for diagnosing ... AcuteKidneyInjury #Nephrology
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Na <20: Extra-renal ... Urine Na >30: Renal ... Cirrhosis, Nephrotic syndrome ... Hyponatremia #algorithm #diagnosis ... #sodium #low #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Epithelial Cells Renal ... cell epithelial sodium ... of epithelial sodium ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
- Differential Diagnosis ... mOsm/kg - Implies renal ... , Cushing syndrome ... Workup #Algorithm #nephrology ... #sodium
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
- Differential Diagnosis ... Algorithm Extra-renal ... loss (Diarrhea) Renal ... #Differential #Diagnosis ... potassium #low #nephrology
Renal Tubular Acidosis (RTA) Diagnosis and Management
 • Distal (type 1) RTA
 • Proximal (type 2)
Renal Tubular Acidosis ... (RTA) Diagnosis ... and Management ... 4) RTA #rta #Renal ... #Management #nephrology
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
- Differential Diagnosis ... perspiration Renal ... #Differential #Diagnosis ... #Causes #nephrology ... #sodium #high