22 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
TTP/HUS, HELLP Syndrome ... Pregnancy (AFLP) Three syndromes ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... Hemolysis, Elevated Liver ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... LungDisease #CTILD #Diagnosis ... #Differential #Comparison ... #Table #Pulmonary ... #Rheumatology #
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... Kasabach-Merritt syndrome ... deficiency • Liver ... #hematology #rheumatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
) • Advanced Liver ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Dermatomyositis Anti-LKM (liver ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... Associations #diseases #diagnosis ... #table #rheumatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
trigger - Direct skin ... Disorientation, vertigo Diagnostic ... Cold #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
heliotrope, shawl sign ... Associated Features: Diagnosis ... #differential #diagnosis ... #comparison #rheumatology ... #table
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... disease and ILD • Liver ... Liver biopsies show ... Dermatomyositis #rheumatology ... #dermatology #diagnosis