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diagnosis acute kidney aki differential injury nephrology blood management renal treatment algorithm bun causes classification creatinine drugs emesis failure gastroenterology
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal PRE-RENAL Impaired perfusion: •
Prerenal, Renal, and Postrenal ... Injury #Prerenal #Postrenal
BUN/Creatinine ratio differentiate between acute and chronic renal disease. Prerenal azotemia appears when there is poor renal
Postrenal azotemia ... azotemia or late postrenal
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
nephritis (AIN) Postrenal
Medications causing Acute Kidney Injury (AKI) Prerenal: • Dehydration: Diuretics • Altered intrarenal autoregulation: ACEIs / ARBs,
, methotrexate Postrenal
Hematuria in Post-Renal Transplant Patient Prevalence up to 12% in the postrenal transplant patient • Bacterial: Escherichia
to 12% in the postrenal
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Prerenal: • Due to true volume loss or decreased
glomerulonephritis) Postrenal
Acute Kidney Injury - Differential Diagnosis Framework PRERENAL: - Intrarenal vasoconstriction-hemodynamically mediated - Systemic vasodilation - Volume
underlying cause POSTRENAL
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
prerenal azotemia or postrenal
Acute Kidney Injury (AKI) - Management Principles Prerenal - Correct hemodynamic derangements: • If low preload →
causative medication Postrenal
Causes of Nausea and Vomiting - Differential Diagnosis Framework Chemoreceptor Trigger Zone/Area Postrema: • Drugs: - Chemo agents -
Trigger Zone/Area Postrema
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